daosin

Daosin is a branded dietary supplement containing the enzyme diamine oxidase (DAO), which is responsible for breaking down histamine in the intestine. It is used for the dietary management of DAO deficiency and histamine intolerance, conditions where insufficient DAO activity leads to elevated levels of histamine from food, resulting in symptoms such as migraines, digestive issues, and skin reactions. The supplement provides exogenous DAO—typically derived from pig kidney protein extract—to complement or restore deficient endogenous enzyme activity. By increasing intestinal DAO levels when taken before meals, Daosin enhances the breakdown of ingested histamine and may reduce symptoms associated with histamine intolerance[1][5][6][7].

Brand names

Daosin

Other names

DAO