Drug intelligence / Profile preview

DBI-002 probiotic gel

Development stage
Phase 2
Lead developer
DermBiont, Inc.
Modality
Live Biotherapeutic Products → Microbiome Therapeutics
Administration
Topical
01

Overview

DBI-002 probiotic gel is an investigational topical live biotherapeutic product (LBP) developed by DermBiont for the treatment of fungal skin infections, including tinea versicolor, onychomycosis, and interdigital tinea pedis. The formulation consists of a topical aqueous gel containing the live probiotic bacterium *Janthinobacterium lividum*. Its mechanism of action involves the reduction of *Malassezia* species, the fungi responsible for tinea versicolor, likely through the production of antifungal metabolites such as violacein. DBI-002 has been evaluated in a Phase 2a randomized, double-blind, dose-escalating trial (NCT04937920) to assess its safety and antimicrobial efficacy in adults with tinea versicolor.

Other names
DBI-002 ProbioticDBI002 ProbioticDBI 002 ProbioticDBI-002 Probiotic GelDBI002 Probiotic GelDBI 002 Probiotic Gel
02

Targets

PRR (Pattern recognition receptors)

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