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DC-CIK01 (Ever Supreme Bio-Technology)

Development stage
Unknown
Lead developer
Ever Supreme Bio-Technology
Modality
Dendritic Cell Vaccines → Immune Effector Cells → Other Cell Types → Cell Therapies
Administration
Intravenous
01

Overview

DC-CIK01 is an autologous cell therapy developed by Ever Supreme Bio-Technology, combining dendritic cells (DCs) and cytokine-induced killer (CIK) cells. This dual-component therapy leverages the antigen-presenting capabilities of DCs to prime the immune system against tumor-associated antigens, while the CIK cells (predominantly CD3+CD56+ T cells) provide potent, non-MHC-restricted cytotoxicity against tumor cells. The CIK component typically recognizes tumor cells via the NKG2D receptor. DC-CIK01 is primarily utilized in Taiwan, where it has received approval under the "Regulations Governing the Application of Cell Therapy" for the treatment of various Stage 4 solid tumors, including lung, liver, and colorectal cancers. The therapy is designed to enhance the patient's anti-tumor immunity, potentially improving survival outcomes and quality of life in advanced-stage disease.

Other names
dendritic cell-cytokine induced killer cell therapyDC-CIK therapy
02

Targets

MICB (Major histocompatibility complex class i-related protein B)CCR5 (C-C chemokine receptor type 5)ICAM1 (Intercellular Adhesion Molecule 1)

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