DC161-DP0292

DC161-DP0292 is an **aqueous oral spray saliva substitute** developed as a treatment for **drug-induced xerostomia** (dry mouth) in adults with hyposalivation. Its mechanism is based on **mechanical and physicochemical lubrication** of the oral mucosa, acting as an artificial saliva to relieve symptoms such as mouth dryness, difficulty swallowing, and speaking. The formulation includes **glycerol, povidone K30, xanthan gum, potassium chloride, xylitol, potassium dihydrogen phosphate, benzylic alcohol, water, and macroglycerol 40 hydroxystearate**. Clinical studies show it provides **fast and long-acting symptomatic relief** and is well-tolerated, with high acceptability for taste, texture, and lubricating effect compared to comparator sprays. It does not act via a pharmacological receptor or enzyme, but recreates the physical actions of saliva, making it a symptomatic, not disease-modifying, therapy[1][2][3][5][6].

Brand names

Elgydium Clinic Dry Mouth

Other names

DC161-DP0292DC-161-DP0292DC 161-DP0292DC161 oral spray (when referring to specific formulation)