Drug intelligence / Profile preview

DC50292A

Development stage
Phase 1
Lead developer
China Resources Double-Crane Pharmaceutical
Modality
Small Molecules
Administration
Oral
01

Overview

DC50292A is an investigational small molecule drug being developed as an oral tablet for the treatment of advanced or metastatic solid tumors with methylthioadenosine phosphorylase (MTAP) deletion. It is currently under evaluation in Phase 1 clinical trials for its safety, tolerability, pharmacokinetics, and preliminary anti-tumor efficacy in patients with MTAP-deficient cancers. The drug’s mechanism of action and molecular target have not been publicly disclosed; it is intended as a targeted therapy for patients whose tumors exhibit loss of MTAP, which is a common genetic alteration in certain difficult-to-treat cancers.

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