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DCB07010 + trivalent influenza vaccine
- Development stage
- Unknown
- Lead developer
- Advagene
- Modality
- Recombinant Proteins and Enzymes, Vaccines & Immunotherapeutics
- Administration
- Intranasal
01
Overview
DCB07010 + trivalent influenza vaccine is an investigational intranasal vaccine candidate developed by Advagene Biopharma. It consists of trivalent inactivated influenza virus hemagglutinin (HA) antigens co-administered with DCB07010, a proprietary protein-based adjuvant. DCB07010 is derived from a prokaryotic organism, specifically a modified version of the heat-labile enterotoxin (LT) from *Escherichia coli*. This combination is designed to enhance both mucosal (secretory IgA) and systemic (IgG) immune responses against seasonal influenza. By utilizing the intranasal route, the vaccine aims to provide a needle-free alternative that stimulates immunity at the primary site of viral entry. The product has been evaluated in Phase 1 clinical trials to assess safety, tolerability, and immunogenicity in healthy adults.
- Other names
- DCB07010 adjuvant with influenza vaccineDCB-07010 adjuvant with influenza vaccineDCB 07010 adjuvant with influenza vaccineDCB07010 + TIV
02
Targets
HA (Hemagglutinin)
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