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DCvac
- Development stage
- Phase 2
- Lead developer
- Shenzhen Geno-Immune Medical Institute
- Modality
- Dendritic Cell Vaccines → Immune Effector Cells → Other Cell Types → Cell Therapies, Vaccines & Immunotherapeutics
- Administration
- Injection
01
Overview
DCvac is an autologous, engineered dendritic cell vaccine developed by the Shenzhen Geno-Immune Medical Institute. It is designed for the treatment of multiple myeloma and plasmacytoma, specifically as a remission maintenance therapy for patients who have achieved a partial or complete response following prior treatments. The therapy involves the ex vivo modification and maturation of patient-derived dendritic cells (DCs), which are then re-administered to the patient. These engineered DCs are intended to present tumor-associated antigens to the patient's immune system, thereby stimulating and expanding a targeted T-cell response to eliminate residual malignant plasma cells and prolong remission.
- Brand names
- DCVAC/PCaDCVAC/OvCaDCVAC/LuCa
- Other names
- Engineered Dendritic Cell VaccinesDC vaccinesImmune-modified DC vaccines
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