Drug intelligence / Profile preview

DD15

Development stage
Preclinical
Lead developer
D&D Pharmatech
Modality
Peptides
Administration
Subcutaneous
01

Overview

DD15 is a preclinical-stage injectable peptide multi-agonist developed by D&D Pharmatech for the treatment of obesity. It is designed to simultaneously target three key metabolic pathways: the glucagon-like peptide-1 (GLP-1) receptor, the glucose-dependent insulinotropic polypeptide (GIP) receptor, and the glucagon (GCG) receptor. By acting as a triple agonist, DD15 aims to leverage the synergistic effects of these pathways—appetite suppression and slowed gastric emptying (GLP-1), improved insulin sensitivity and lipid metabolism (GIP), and increased energy expenditure (GCG)—to achieve superior weight loss and metabolic outcomes compared to single or dual-receptor agonists.

02

Targets

GLP1R (GLP-1R)GCGR (Glucagon receptor)GIPR (Gastric inhibitory polypeptide receptor)

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