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DDD-024 is a preclinical-stage small molecule drug being developed by Daya CNS for the treatment of substance use disorders, specifically targeting methamphetamine, amphetamine, and opioid addiction. The compound is part of a proprietary non-opioid pyridoindole platform invented by Dr. Parthasarathi Rajagopalan. DDD-024 has demonstrated efficacy in preclinical rat models of methamphetamine self-administration, showing potential to reduce drug-seeking behavior without the adverse effects or abuse potential associated with opioid-based therapies. As of early 2024, the drug is in the pre-IND stage of development.
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