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DE-110 is a small molecule drug developed by Santen Pharmaceutical for ophthalmic use. It acts as an agonist of the glucocorticoid receptor (GR), making it a glucocorticoid receptor agonist. The primary indication under investigation has been dry eye syndromes, where its anti-inflammatory properties are expected to provide therapeutic benefit. Clinical development reached Phase 2 for dry eye syndromes[1].
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