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DE-111 is an investigational ophthalmic solution developed for the treatment of open-angle glaucoma and ocular hypertension. Its primary purpose is to lower intraocular pressure (IOP) in affected patients. The specific mechanism of action, molecular target, and active ingredient for DE-111 have not been disclosed in publicly available sources as of May 2025. Clinical evaluation has focused on safety and efficacy in reducing IOP in a multicenter, open-label study involving patients with these conditions[6].
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