Drug intelligence / Profile preview

DE3

Development stage
Phase 1
Lead developer
LYS PHARMA
Modality
Small Molecules
Administration
Oral
01

Overview

DE3 is a high-potency omega-3 dietary supplement developed by LYS PHARMA in partnership with the U.S.-based company PRN (Physician Recommended Nutriceuticals). Specifically formulated for the management of dry eye disease, DE3 contains eicosapentaenoic acid (EPA) and docosahexaenoic acid (DHA) in a re-esterified triglyceride (rTG) form. This formulation is designed to enhance absorption and bioavailability compared to standard ethyl ester omega-3 products. DE3 works by modulating the inflammatory response on the ocular surface and improving the quality of the lipid layer of the tear film. Its efficacy is supported by clinical data, including double-blind, placebo-controlled trials (DBDCT), which demonstrate improvements in tear osmolarity and symptomatic relief for patients with dry eyes.

Brand names
DE3DE-3DE 3Dry Eye Omega-3
Other names
디이3DE3 90 capsulesDE-3 90 capsulesDE 3 90 capsulesDE3 270 capsulesDE-3 270 capsulesDE 3 270 capsules
02

Targets

ALOX5 (Arachidonate 5-lipoxygenase)COXFFAR4 (Free fatty acid receptor 4)

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