Drug intelligence / Profile preview

Debio 1144

Development stage
Preclinical
Lead developer
Debiopharm
Modality
Small Molecules
Administration
Oral
01

Overview

**Debio 1144** is an investigational, orally available small molecule multikinase inhibitor licensed by Debiopharm from Ascepion Pharmaceuticals for oncology indications. It targets several tyrosine kinase oncogenes implicated in cancer growth, demonstrating strong efficacy in preclinical models of solid tumors with a large therapeutic index. Development focuses on cancers prevalent in China, supported by Debiopharm for further advancement in that market, though no clinical trial data or specific indications have advanced beyond preclinical stages.

Other names
Debio 1144Debio1144Debio-1144
02

Targets

MET (Mesenchymal-epithelial transition factor receptor)VEGFR2 (Vascular endothelial growth factor receptor 2)

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