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Decomic
- Development stage
- Unknown
- Lead developer
- Ordain Health Care
- Modality
- Small Molecules
- Administration
- Ophthalmic
01
Overview
Decomic is an ophthalmic combination solution developed by Ordain Health Care (now part of Exeltis) for the treatment of allergic eye diseases and minor eye irritation. It contains phenylephrine hydrochloride (a vasoconstrictor/decongestant), chlorpheniramine maleate (an antihistamine), boric acid (an antiseptic), and hypromellose or carboxymethylcellulose sodium (lubricants). Phenylephrine constricts blood vessels in the conjunctiva to reduce redness and swelling, while chlorpheniramine blocks histamine H1 receptors to alleviate itching and watering. Boric acid helps maintain pH and prevent infection, and the polymeric lubricants provide moisture to soothe dry, irritated eyes.
- Brand names
- Decomic
- Other names
- boric acid + chlorpheniramine maleate + hypromellose + phenylephrine hydrochlorideboric acid + chlorpheniramine maleate + phenylephrine hydrochloride + sodium carboxymethylcellulose
02
Targets
ADRA1A (α1A)HRH1 (Histamine H1 Receptor)
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