Drug intelligence / Profile preview

Deflet

Development stage
Unknown
Lead developer
Droplet Life Science
Modality
Orthosteric Ligands → Classical Binding Small Molecules → Small Molecules
Administration
Oral
01

Overview

Deflet is an oral tablet formulation containing 6 mg of deflazacort, a synthetic glucocorticoid developed by the Indian pharmaceutical company Droplet Life Science. As a prodrug, deflazacort is rapidly converted into its active metabolite, 21-desacetyldeflazacort, which functions as a glucocorticoid receptor agonist. It is indicated for a variety of inflammatory and immune-mediated conditions, including rheumatoid arthritis, asthma, and nephrotic syndrome. Deflet is characterized by a safety profile that potentially offers a lower risk of osteoporosis and growth retardation compared to other corticosteroids due to its reduced impact on calcium metabolism.

Brand names
Deflet
Other names
deflazacort 6 mgdeflazacort6 mgdeflazacort-6 mg
02

Targets

GR (Glucocorticoid receptor)

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