deglucobalhimycin

Deglucobalhimycin is an oligopeptide antibiotic belonging to the class of organic compounds known as oligopeptides (compounds containing a sequence of between three and ten amino acids)[1]. It is a complex molecule with antibacterial properties and is structurally related to glycopeptide antibiotics such as balhimycin and vancomycin but lacks certain sugar moieties ("degluco" indicates removal of glucose units). Its mechanism of action likely involves inhibition of bacterial cell wall synthesis by binding to D-Ala-D-Ala termini in peptidoglycan precursors—similar to other glycopeptide antibiotics—thereby preventing cell wall cross-linking and leading to bacterial cell death[1]. Deglucobalhimycin has been studied primarily in research settings for its antibacterial activity.

Other names

(1r,2s,18r,19r,22r,25r,28r,40r)-2-((2r,4r,6r)-4-amino-5,5-dihydroxy-4,6-dimethyloxan-2-yl)oxy-22-(2-amino-2-oxoethyl)-5,15-dichloro-18,32,35,37,48-pentahydroxy-19-(((2r)-4-methyl-2-(methylamino)pentanoyl)amino)-20,23,26,42,44-pentaoxo-7,13-dioxa-21,\n 24,\n 27,\n 41,\n 43-pentazaoctacyclo(26.14.2.23,\n 6.214,\n 17.18,\n 12.129,\n 33.010,\n 25.034,\n39)pentaconta-\n3,\n5,\n8,\n10,\n12(48),\n14,\n16,\n29(45),\n30\n32\n34(39),\n35\n37\n46\n49-pentadecaene-\n40-carboxylic acid[2]