dehydroepiandrosterone + triiodothyroacetic acid

A topical combination of **dehydroepiandrosterone (DHEA)**, a steroid hormone and precursor of sex hormones, and **triiodothyroacetic acid (TRIAC)**, a thyroid hormone analog, that is designed to **stimulate collagen synthesis and treat corticosteroid-induced and other forms of skin atrophy**. The combination has demonstrated a **synergistic effect** in preclinical and early pharmacokinetic studies, stimulating type I procollagen synthesis in human skin more effectively than either agent alone. This combination is intended primarily for **topical administration** to the skin, offering a potential treatment for dermatological conditions such as atrophoderma resulting from corticosteroid use, photoaging, or aging. The mechanism is thought to involve hormone receptor-mediated signaling pathways in skin fibroblasts to enhance extracellular matrix production[1][5][7].

Other names

DHEA + TRIACdehydroandrosterone + triiodothyroacetic aciddehydroepiandrosterone + TRIAC