Drug intelligence / Profile preview

DEM201

Development stage
Unknown
Lead developer
DEM Biopharma
Modality
Antibody-Based Therapeutics
01

Overview

DEM201: sourced facts only. name: "DEM201 was selected as a clinical candidate and is specific for human SMAGP with sub-nanomolar (nM) affinity." [DOI:10.1158/1538-7445.am2025-4254]; target: "DEM201 was selected as a clinical candidate and is specific for human SMAGP with sub-nanomolar (nM) affinity." [DOI:10.1158/1538-7445.am2025-4254]; developer: "DEM BioPharma, Inc., Cambridge, MA." [DOI:10.1158/1538-7445.am2025-4254]; modality: "Development of DEM201, a blocking antibody against SMAGP, a novel “Don′t Eat Me” signal overexpressed in cancer" [DOI:10.1158/1538-7445.am2025-4254]; stage: "In vivo, DEM201 significantly inhibited the growth of SMAGP-expressing RKO tumor xenografts." [DOI:10.1158/1538-7445.am2025-4254]

02

Targets

SMAGP (Small cell adhesion glycoprotein)

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