demoxytocin

Demoxytocin is a synthetic peptide analogue of the hormone oxytocin, developed to induce labor, promote lactation, and prevent or treat puerperal (postpartum) mastitis. It acts as an oxytocic agent by stimulating uterine smooth muscle contraction and promoting milk ejection from the mammary glands. Compared to oxytocin, demoxytocin is more potent and has a longer half-life. Unlike oxytocin, which is administered intravenously, demoxytocin is given as a buccal tablet. Its mechanism involves increasing calcium ion content in smooth muscle cells to enhance contractility. The drug was first synthesized in 1960 and introduced into clinical practice in 1971 by Sandoz; it remains marketed in several European countries including Italy, Czech Republic, and Poland[1][2][3][4][5].

Brand names

SandopartOdeaxSandopral

Other names

desaminooxytocindeaminooxytocin1-(3-mercaptopropanoic acid)oxytocinDemoxitocinaDemoxytocineDemoxytocinum