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Dendrobii caulis refers to the stem of plants from the genus Dendrobium, particularly Dendrobium officinale, widely used in traditional Chinese medicine and as a functional food in East Asia[2][3]. It is consumed for its purported health benefits including anti-inflammatory, antinociceptive (pain-relieving), and eye-protective effects[2][3][5]. Recent research has shown that extracts of dendrobii caulis can relieve neuropathic pain by modulating the transient receptor potential vanilloid 1 receptor (TRPV1) in the spinal cord[2]. The plant contains various bioactive compounds such as polysaccharides and picrotoxane-type sesquiterpenes; these are believed to contribute to its pharmacological activities including anti-inflammatory action via inhibition of proinflammatory cytokines like TNF-α and IL-1β[3], antioxidant effects, cytoprotection against oxidative stress in retinal cells[5], and possible anticancer properties. It is also marketed as a dietary supplement for general wellness or specific uses such as improving vision or nourishing yin energy according to traditional concepts[4].
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