Drug intelligence / Profile preview

DendroCore

Development stage
Preclinical
Lead developer
DendroPharm
Modality
Polymer-based Nanoparticles → Nanoparticles → Drug Delivery Systems
01

Overview

DendroCore is a highly sulfated, multivalent dendritic nanomaterial developed by DendroPharm that acts as a potent heparin analogue. It is designed for the treatment of inflammation and thrombosis by leveraging its extremely tight binding affinity for P-selectin and L-selectin. This interaction prevents the adhesion of leukocytes to inflamed vascular tissue and inhibits the formation of thrombi. As a product of DendroPharm's advanced nanocarrier technology platform, DendroCore is currently in preclinical development, offering a novel approach to targeting selectin-mediated biological processes with high specificity and multivalency.

Brand names
DendroCore
Other names
heparin analoguedendritic nanomaterial-based heparin analogue
02

Targets

SELP (P-selectin)SELL (L-selectin)

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