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Dengzhan Xixin Formula Granule
- Development stage
- Preclinical
- Lead developer
- Guizhou Yibai Pharmaceutical
- Administration
- Oral
01
Overview
Dengzhan Xixin Formula Granule (灯盏细辛中药配方颗粒) is a standardized Traditional Chinese Medicine (TCM) preparation developed by Guizhou Yibai Pharmaceutical. It is derived from the aerial parts of *Erigeron breviscapus* (Vaniot) Hand.-Mazz., a perennial herb native to southwestern China. The granule contains a mixture of active flavonoids and caffeoyl derivatives, most notably scutellarin (the primary component of breviscapine), which are recognized for their therapeutic effects on cardiovascular and cerebrovascular systems. Clinically, Dengzhan Xixin preparations are utilized in China for the treatment of acute ischemic stroke, sequelae of cerebral ischemia, coronary heart disease, and angina. As a formula granule, it is intended for use in compounded TCM prescriptions, providing a standardized and convenient alternative to traditional raw herb decoctions.
- Other names
- 灯盏细辛中药配方颗粒Dengzhan XixinErigeron breviscapus formula granule
02
Targets
CA3 (Carbonic anhydrase 3)CMA1 (Chymase)EGFR (Epidermal growth factor receptor)F7 (Coagulation Factor VII)GRIA1 (AMPA receptor subunit GluA1)SLCO2B1 (Organic anion transporting polypeptide 2B1)PAH (Phenylalanine hydroxylase)PDE10A (Phosphodiesterase 10A)PRKCG (Protein kinase C gamma)SRC (Proto-oncogene tyrosine-protein kinase Src)GUSB (Beta-glucuronidase)
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