Drug intelligence / Profile preview

Dentaid lozenge

Development stage
Unknown
Lead developer
Dentaid
Modality
Small Molecules
Administration
Topical
01

Overview

The Dentaid lozenge is a topical gustatory salivary stimulant containing 1% malic acid, developed by Dentaid, S.L. (Spain) for the management of xerostomia (dry mouth), particularly in patients with primary Sjögren's syndrome. It functions by stimulating taste receptors on the tongue, which triggers a neural reflex that increases the secretion of saliva from the salivary glands. Unlike systemic sialagogues such as pilocarpine, the Dentaid lozenge acts locally and has been shown in clinical trials to improve salivary flow rate, buffering capacity, and oral health-related quality of life with a favorable safety profile. It is part of the Xeros Dentaid product line designed specifically for individuals suffering from dry mouth.

Brand names
Xeros Dentaid
Other names
malic acid lozengeDentaid malic acid lozenge
02

Targets

TAS2R (Taste receptor type 2 family)

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