Drug intelligence / Profile preview

Dentiline

Development stage
Unknown
Lead developer
Ghimas
Administration
Topical
01

Overview

Dentiline is a topical gingival gel developed by Ghimas, primarily indicated for the relief of symptoms associated with teething in infants and general gum irritation. The formulation is based on a combination of botanical extracts, including *Aloe barbadensis*, *Chamomilla recutita* (Chamomile), and *Boswellia serrata*. These ingredients work synergistically to provide a soothing effect, reduce inflammation, and form a protective film over the oral mucosa. *Boswellia serrata* extract is known for its ability to inhibit the 5-lipoxygenase (5-LOX) enzyme, which plays a key role in the inflammatory cascade by reducing the production of leukotrienes. Dentiline is commercialized as a nutraceutical-based oral care product, offering a botanical approach to managing oral discomfort and protecting sensitive gingival tissues.

Brand names
Dentiline
Other names
Dentiline Gingival GelDentiline Gel
02

Targets

COXALOX5 (Arachidonate 5-lipoxygenase)

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