Clinical trials
Full profile accessFollow clinical development from study design and recruitment through results.
- Trial phase
- Status
- Readouts
Drug intelligence / Profile preview
deoxyepinephrine
- Development stage
- Preclinical
- Modality
- Small Molecules
- Administration
- Ophthalmic, Intravenous
01
Overview
Deoxyepinephrine (also known as epinine or N-methyldopamine) is a naturally occurring catecholamine and sympathomimetic agent structurally related to dopamine and epinephrine. It acts as a non-selective agonist at dopamine receptors (D1 and D2), alpha-adrenoceptors (alpha-1 and alpha-2), and beta-adrenoceptors (beta-1 and beta-2). Its pharmacological effects include vasoconstriction via alpha-receptor stimulation, increased heart rate through beta-receptor activation, diuresis via renal dopamine receptor activation, and modulation of prolactin secretion. Deoxyepinephrine is the active metabolite of ibopamine—a drug used in the management of congestive heart failure—and has been investigated for cardiovascular indications as well as potential intraoperative ophthalmic use due to its mydriatic effect[1][4][6][7].
- Brand names
- epinine
- Other names
- deoxyepinephrineepinineN-methyldopaminedesoxyepinephrine
02
Targets
ADRB2 (β2)ADRA2A (α2A)DRD1 (Dopamine D1 Receptor)ADRA1A (α1A)DRD2 (Dopamine D2 Receptor)ADRB1 (β1)
Beyond the preview
Go deeper on deoxyepinephrine.
Explore the evidence, development activity, and competitive landscape with Gosset’s full data platform.
Indications & development
Full profile accessExplore development by indication, patient population, and geography.
- Indications
- Development status
- Countries
Licensing & deals
Full profile accessTrace asset ownership, licensing agreements, and commercial partnerships.
- Partners
- Deal terms
- Milestones
Patents & exclusivity
Full profile accessExplore the patent landscape and regulatory exclusivity around an asset.
- Patents
- Expiration dates
- Exclusivity
Competitive landscape
Full profile accessCompare development programs by target, modality, and indication.
- Competing assets
- Targets
- Development stage
Research & analysis
Full profile accessConnect source evidence and development news to your research questions.
- Publications
- News
- Analysis
Bring the full picture into focus.
See how Gosset can support your research on deoxyepinephrine.