Depex-P

Depex-P is a combination syrup formulated with chlorpheniramine maleate, dextromethorphan hydrobromide, and phenylephrine hydrochloride. It is developed by Alde Medi Impex and is marketed for the relief of symptoms associated with the common cold, allergies, and upper respiratory tract infections, such as dry cough, nasal congestion, runny nose, and sneezing. Chlorpheniramine maleate is a first-generation antihistamine that acts as a competitive antagonist of the histamine H1 receptor, reducing allergic symptoms. Dextromethorphan hydrobromide is an antitussive agent that acts as a sigma-1 receptor agonist and a non-competitive NMDA receptor antagonist, suppressing the cough reflex in the brain. Phenylephrine hydrochloride is a selective alpha-1 adrenergic receptor agonist that acts as a decongestant by causing vasoconstriction in the nasal passages, thereby reducing swelling and congestion.

Brand names

Depex-PDepex-P syrup

Other names

CPM + dextromethorphan + phenylephrineCPM plus dextromethorphan plus phenylephrinechlorpheniramine + dextromethorphan + phenylephrinechlorpheniramine maleate + dextromethorphan hydrobromide + phenylephrine hydrochloridechlorpheniramine maleate plus dextromethorphan plus phenylephrine syrup