Drug intelligence / Profile preview

Depigoid Grass + Birch Mix

Development stage
Unknown
Lead developer
Leti Pharma
Modality
Sublingual Immunotherapy → Allergy Immunotherapy → Therapeutic Vaccines → Vaccines & Immunotherapeutics, Subcutaneous Immunotherapy → Allergy Immunotherapy → Therapeutic Vaccines → Vaccines & Immunotherapeutics
Administration
Subcutaneous
01

Overview

Depigoid Grass + Birch Mix is a depigmented, polymerized mixed pollen allergen extract developed by LETI Pharma (a subsidiary of Laboratorios LETI) for subcutaneous allergen immunotherapy (SCIT). It combines allergens from grass and birch pollen that have been chemically modified through depigmentation and polymerization to reduce their IgE-binding capacity (allergenicity) while preserving their ability to induce a protective immune response (immunogenicity). The extract is adsorbed onto aluminium hydroxide for sustained release. It is indicated for the treatment of allergic rhinitis, allergic rhinoconjunctivitis, and mild intermittent asthma in patients sensitized to both grass and birch pollen. The product aims to modulate the immune system to reduce hypersensitivity and induce long-term allergen tolerance.

Brand names
Depigoid
Other names
Depigoid Grass / Birch Mix
02

Targets

Birch sIgE (Birch pollen-specific immunoglobulin E)sIgE (Grass pollen-specific immunoglobulin E)Allergen-specific B-cell receptor and T-cell receptor

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