Drug intelligence / Profile preview

Depigoid Grass Mix

Development stage
Unknown
Lead developer
Leti Pharma
Modality
Sublingual Immunotherapy → Allergy Immunotherapy → Therapeutic Vaccines → Vaccines & Immunotherapeutics, Subcutaneous Immunotherapy → Allergy Immunotherapy → Therapeutic Vaccines → Vaccines & Immunotherapeutics
Administration
Subcutaneous
01

Overview

Depigoid Grass Mix is a subcutaneous allergen immunotherapy (SCIT) product developed by LETI Pharma (a subsidiary of Laboratorios LETI). It consists of chemically modified (depigmented) and polymerized allergen extracts derived from grass pollen. The modification process involves treating the allergens with glutaraldehyde to reduce their IgE-binding capacity (allergenicity) while preserving their ability to induce a protective immune response (immunogenicity). This modification allows for a safer and more rapid up-dosing schedule, such as a preseasonal rush scheme. The product is indicated for the treatment of allergic rhinitis, allergic rhinoconjunctivitis, and allergic asthma in patients sensitized to grass pollen, and it is approved for use in adults and children aged 5 years and older.

Brand names
Depigoid Grass Mix
Other names
Depigoiddepigmented grass pollen extractgrass pollen allergens
02

Targets

TCR (T cell antigen receptor complex)BCR (Immunoglobulin G B Cell Receptor)

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