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Depiwhite is a range of dermatological skin-lightening products developed by Laboratoire Dermatologique ACM, primarily indicated for the treatment of hyperpigmentation disorders such as melasma, liver spots, and post-inflammatory hyperpigmentation. The formulations typically utilize a combination of active ingredients including kojic acid, vitamin C (ascorbyl glucoside), niacinamide, and plant-derived extracts to inhibit tyrosinase activity and melanin transfer. Unlike traditional treatments like hydroquinone, Depiwhite is marketed as a cosmetic or cosmeceutical alternative with a focus on high dermatological tolerance and efficacy in reducing the intensity of brown spots and evening skin tone. Clinical studies have evaluated its performance against 4% hydroquinone, demonstrating significant improvements in the Modified Melasma Area and Severity Index (mMASI) with superior skin tolerability.
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