deproteinized calf blood extract

Deproteinized calf blood extract (DCBE) is a protein-free hemodialysate derived from the blood of veal calves through ultrafiltration. It contains a complex mixture of low molecular weight components, including amino acids, small peptides, and oligosaccharides. The drug acts as a metabolic enhancer by improving the transport and utilization of oxygen and glucose, thereby stimulating intracellular ATP synthesis and aerobic glycolysis. These effects are particularly beneficial under hypoxic or nutrient-deficient conditions, promoting tissue repair, regeneration, and neuroprotection. DCBE is utilized across various therapeutic areas: in ophthalmology as eye drops for dry eye disease and corneal epithelial repair; in neurology for post-stroke cognitive impairment and diabetic peripheral polyneuropathy; and in vascular medicine for peripheral arterial occlusive disease. While widely used in Russia, China, and Eastern Europe, its regulatory status and clinical evidence base vary internationally.

Brand names

ActoveginSolcoseryl

Other names

deproteinized calf blood hemodialysateprotein-free calf blood extractDCBE小牛血去蛋白提取物