Drug intelligence / Profile preview

Dermadexin

Development stage
Unknown
Lead developer
Cipher Pharmaceuticals
Modality
Drug Delivery Systems
Administration
Topical
01

Overview

Dermadexin is a patent-protected topical barrier-repair cream containing the active ingredient P3GCM, a biolipid–niacin complex designed to alleviate symptoms of inflammatory skin conditions such as seborrheic dermatitis, eczema, and facial dermatitis. It works through dual mechanisms of action by restoring the skin barrier function to prevent microbial invasion and reducing irritation, redness, scaling, and itching without the risks associated with topical steroids. Approved as a Class III medical device in the European Union in 2014, it was developed by Astion Pharma and acquired by Cipher Pharmaceuticals, with a 510(k) submission accepted by the FDA in 2015 targeting seborrheic dermatitis on the scalp, face, and torso.[4][7][8][10][12][18]

Brand names
DermadexinHelioclin Dermatitis SD Cream
Other names
P3GCMP-3GCMP 3GCM
02

Targets

NF-κBFAAH

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