Dermal Advantage

Dermal Advantage is a brand of high-potency topical urea formulations, typically containing 40% or 50% urea, used as a potent keratolytic agent. It is designed to treat hyperkeratotic skin conditions and dystrophic nail disorders by increasing the water-binding capacity of the stratum corneum and facilitating the denaturation and solubilization of proteins like keratin. This process promotes the debridement of necrotic tissue and the softening of thickened skin or nails, making it effective for conditions such as psoriasis, xerosis, ichthyosis, and the non-surgical removal of damaged nails. It is generally marketed as a professional-grade or prescription-strength topical treatment.

Brand names

Dermal Advantage

Other names

ureacarbamide