Drug intelligence / Profile preview

Dermalleve

Development stage
Discontinued
Lead developer
Advanced Derm Solutions
Modality
Small Molecules
Administration
Topical
01

Overview

**Dermalleve** was a Calgenex over-the-counter topical cream containing **hydrocortisone 1%**, a low-potency topical corticosteroid. It was introduced for symptomatic treatment of inflammatory, pruritic skin conditions including psoriasis, eczema, and seborrheic dermatitis. Hydrocortisone activates glucocorticoid receptors in the skin, suppressing inflammatory signaling and helping reduce erythema, irritation, and itch. The product also incorporated non-drug skin conditioners and emollients. Publicly available information is historical; Dermalleve is distinct from the currently marketed similarly spelled product Dermeleve.

Brand names
Dermalleve
02

Targets

GR (Glucocorticoid receptor)

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