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Dermatophagoides pteronyssinus allergen extract
- Development stage
- Unknown
- Lead developer
- Roxall Medizin
- Modality
- Sublingual Immunotherapy → Allergy Immunotherapy → Therapeutic Vaccines → Vaccines & Immunotherapeutics, Subcutaneous Immunotherapy → Allergy Immunotherapy → Therapeutic Vaccines → Vaccines & Immunotherapeutics
- Administration
- Sublingual
01
Overview
SLI-RX-DPT is a sublingual immunotherapy (SLIT) being developed by ROXALL Medizin GmbH for the treatment of house dust mite allergies. [1] It consists of a native allergen extract from the house dust mite *Dermatophagoides pteronyssinus*, formulated as a sublingual spray. [1, 17] The therapeutic principle is hyposensitization, where repeated administration of the allergen aims to induce immunological tolerance and reduce the allergic response. [1] SLI-RX-DPT is under evaluation in a Phase II/III clinical trial to assess its efficacy and safety in patients with moderate to severe allergic rhinitis and/or rhinoconjunctivitis. [1, 16]
- Other names
- native allergen extract from Dermatophagoides pteronyssinus
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