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Dermavest is a **biologic tissue substitute and regenerative wound care product** developed by AediCell for replacement or supplementation of damaged or inadequate integumental tissue. It is derived from **particularized, decellularized human placental tissue extracellular matrix** sourced from amniotic and chorionic membrane, umbilical cord, and placental disc. The matrix contains structural and signaling components such as **collagen, proteoglycans, polysaccharides, and endogenous cytokines and growth factors**, and functions primarily as an **extracellular scaffold** that supports cell attachment, infiltration, proliferation, and tissue repair rather than acting through a single defined receptor target. Dermavest has been positioned for management of chronic and acute wounds including **diabetic ulcers, pressure ulcers, venous ulcers, burns, trauma wounds, surgical wounds, and post-Mohs surgery defects**. It is described as shelf-stable at room temperature for up to four years and has been assigned HCPCS code Q4153.
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