Drug intelligence / Profile preview

Derris scandens

Development stage
Unknown
Administration
Oral, Topical
01

Overview

Derris scandens (Roxb.) Benth. is a medicinal plant belonging to the Fabaceae family that has been used as an active ingredient in Thai traditional medicine for pain treatment. The dried stem powder and ethanolic extract are recommended in Thailand's National List of Essential Medicines (NLEMs) for musculoskeletal pain treatment as herbal medicine[1]. The plant is characterized by a high content of flavonoids and isoflavonoids. Clinical studies have shown that D. scandens may be considered as an alternative for musculoskeletal pain reduction, with efficacy comparable to nonsteroidal anti-inflammatory drugs (NSAIDs)[1]. Its stems are traditionally used as an expectorant, antitussive, diuretic, antidysentery treatment, and for muscle ache relief[5]. Research has demonstrated that D. scandens possesses anti-inflammatory, analgesic, immunomodulating, and blood pressure regulating properties, without the side effects associated with long-term use of steroids and NSAIDs[4]. It is considered non-toxic even at high doses and functions as a free radical scavenger and antioxidant[4].

Brand names
Herbal One Derris Scandens Extract
Other names
derris scandensDerris scandens (Roxb.) Benth.Jewel vineGonjThao-wan-priangHog Creeper VineDS
02

Targets

AKT1 (Proto-oncogene serine/threonine-protein kinase Akt1)

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