Drug intelligence / Profile preview

Desentum cat allergy hypoallergen

Development stage
Preclinical
Lead developer
Desentum
Modality
Recombinant Proteins and Enzymes
Administration
Subcutaneous
01

Overview

Desentum's cat allergy hypoallergen is a recombinant protein-based therapeutic candidate currently in preclinical development for the treatment of cat allergy. Developed using Desentum's proprietary recombinant hypoallergen platform, the product is designed for subcutaneous allergen immunotherapy (AIT). The mechanism involves the use of modified cat allergens that maintain the ability to induce T-cell-mediated immune tolerance while exhibiting significantly reduced IgE-binding capacity. This 'hypoallergenic' profile is intended to improve the safety and efficacy of desensitization compared to traditional allergen extracts by minimizing the risk of systemic allergic reactions, such as anaphylaxis, during the treatment course.

Other names
Cat allergy hypoallergenDesentum cat allergy program
02

Targets

Fel d 1-specific TCR (Fel d 1-specific T-cell receptor)Fel d 1-specific immunoglobulin E

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