deslorelin

Deslorelin is a synthetic nonapeptide analogue of gonadotropin-releasing hormone (GnRH), classified as a GnRH superagonist or LHRH agonist. It acts by binding to and activating pituitary GnRH receptors, initially causing a surge in luteinizing hormone (LH) and follicle-stimulating hormone (FSH) secretion. With continuous administration, it desensitizes these receptors, leading to suppression of sex hormones such as testosterone and estradiol. This results in reversible inhibition of reproductive function. Deslorelin is primarily used in veterinary medicine for chemical castration, management of adrenocortical disease in ferrets, benign prostatic hyperplasia in dogs, induction of ovulation in horses, suppression of reproductive behaviors in birds and small mammals, and temporary contraception[1][2][3][5][6].

Brand names

SuprelorinSuprelorin-FOvuplantSucromate Equine

Other names

DeslorelinaDeslorelineDeslorelinumSomagard