desmodium adscendens extract

**Desmodium adscendens extract** is a botanical preparation derived from the leaves of the plant *Desmodium adscendens*, traditionally used in West Africa, South America, and increasingly in Europe for medicinal purposes. It is primarily indicated as a hepatoprotective agent for liver health, especially during medication or chemotherapy, but is also noted for antispasmodic, antihistamine, antioxidant, antimicrobial, anti-inflammatory, immune-stimulating, and neurological effects[2][3]. The extract’s pharmacological activity is attributed to saponosides (purifying, diuretic), flavonoids (anti-inflammatory, immune stimulatory, antioxidant), phenylethylamines, indole-3-alkylamines, triterpenoid saponins (soyasaponin I and III, dehydrosoyasaponin I), and others[3]. Its mechanism of action includes interaction with cytochrome P450 enzymes in the liver (notably CYP2B1/2B2 and CYP2E), which can lead to changes in drug metabolism and potential herb-drug interactions[1][3]. It is usually administered orally, in capsule or ampoule form, and is marketed as a standardized extract in saponosides to ensure consistency of active ingredient levels[2].

Other names

desmodium adscendensDesmodium adscendens (Sw) DCDAdesmodium extract