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Desvancosaminyl vancomycin is a synthetic derivative of the glycopeptide antibiotic vancomycin, in which the vancosamine sugar moiety has been removed. It is also referred to as pseudovancomycin or vancomycin pseudoaglycone. This compound is primarily used as an impurity standard and research tool rather than a therapeutic agent. Like its parent compound, it retains the core structure responsible for binding to bacterial cell wall precursors but lacks the vancosamine group, which may alter its antimicrobial activity profile. Desvancosaminyl vancomycin has not been approved for clinical use and remains an experimental molecule[1][4][9].
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