Drug intelligence / Profile preview

deuterated caffeine

Development stage
Preclinical
Lead developer
d9 Designs
Modality
Small Molecules
Administration
Oral, Topical
01

Overview

Deuterated caffeine is a **small molecule** deuterated isotopologue of caffeine in which the nine hydrogen atoms of the 1, 3, and 7 methyl groups are replaced with deuterium. It is being developed by **d9 Designs** for food, beverage, cosmetic, and potential clinical uses. Pharmacologically, it is intended to retain caffeine's core activity as an **adenosine receptor antagonist** while altering CYP1A2-mediated metabolism through deuterium substitution, with reported longer-lasting stimulant effects, potentially lower dose requirements, and reduced exposure to downstream caffeine metabolites. Publicly described potential medical applications include **apnea in premature infants** and use as an **analgesic adjuvant in pain management**.

Brand names
Deura9Deura-9Deura 9
Other names
deuterated caffeinecaffeine-d9caffeine-d-9caffeine-d 9d9 caffeined-9 caffeined 9 caffeine
02

Targets

ADORA1 (Adenosine receptor A1 subtype)CYP1A2 (Cytochrome P450 1A2)ADORA2A (Adenosine A₂A Receptor)

Beyond the preview

Go deeper on deuterated caffeine.

Explore the evidence, development activity, and competitive landscape with Gosset’s full data platform.

Clinical trials

Full profile access

Follow clinical development from study design and recruitment through results.

  • Trial phase
  • Status
  • Readouts

Indications & development

Full profile access

Explore development by indication, patient population, and geography.

  • Indications
  • Development status
  • Countries

Licensing & deals

Full profile access

Trace asset ownership, licensing agreements, and commercial partnerships.

  • Partners
  • Deal terms
  • Milestones

Patents & exclusivity

Full profile access

Explore the patent landscape and regulatory exclusivity around an asset.

  • Patents
  • Expiration dates
  • Exclusivity

Competitive landscape

Full profile access

Compare development programs by target, modality, and indication.

  • Competing assets
  • Targets
  • Development stage

Research & analysis

Full profile access

Connect source evidence and development news to your research questions.

  • Publications
  • News
  • Analysis

Bring the full picture into focus.

See how Gosset can support your research on deuterated caffeine.

Explore the full profile

Gosset Free

Get started with Gosset.

Enter your work email and we’ll be in touch with next steps.

Work email preferred.

Book a call