Drug intelligence / Profile preview

dEV-000

Development stage
Preclinical
Lead developer
Shine Out Bio Technology
Modality
Lipid-based Nanoparticles → Nanoparticles → Drug Delivery Systems
Administration
Intranasal
01

Overview

dEV-000 is a preclinical-stage exosome-based therapeutic candidate developed by Shine Out Bio Technology for the treatment of Parkinson's disease and other neurodegenerative disorders. The drug utilizes a specialized exosome delivery platform engineered to cross the blood-brain barrier (BBB) and specifically target neurons. By leveraging the natural transport properties of exosomes, dEV-000 aims to deliver therapeutic payloads directly to affected brain regions, potentially improving efficacy and reducing systemic side effects compared to conventional treatments. Preclinical data indicates promising results in neurodegenerative models, particularly for Parkinson's disease.

02

Targets

DAT (Dopamine plasma membrane transport protein)

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