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dexamethasone + methotrexate
- Development stage
- Unknown
- Lead developer
- Pfizer
- Modality
- Small Molecules
- Administration
- Intrathecal, Intravenous, Intravitreal
01
Overview
Dexamethasone + methotrexate is a drug combination used in various therapeutic contexts, particularly for treating certain autoimmune conditions and cancers. This combination leverages the anti-inflammatory properties of dexamethasone (a corticosteroid) with the immunosuppressive and anti-proliferative effects of methotrexate.
- Other names
- MAD regimenmethotrexate-cytarabine-dexamethasone combination
02
Targets
GR (Glucocorticoid receptor)DHFR (Dihydrofolate reductase)
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