dexamethasone + dipyrone + hydroxocobalamin

**Dexamethasone + dipyrone + hydroxocobalamin** is an injectable combination drug used primarily for the management of acute and chronic inflammatory and pain conditions, such as lumbar sciatic pain and acute joint inflammation. Dexamethasone is a synthetic glucocorticoid with potent anti-inflammatory and immunosuppressive effects, acting through glucocorticoid receptors to modulate gene expression and inflammatory mediator production. Dipyrone (also known as metamizole) is a non-opioid analgesic and antipyretic agent of the pyrazolone class, providing pain relief and reduction of fever through inhibition of prostaglandin synthesis, likely via cyclooxygenase enzymes. Hydroxocobalamin is a biologically active form of vitamin B12 with essential roles in cellular metabolism and neuroprotection, and it may further contribute to neural repair in nerve injury. The combination is under investigation in parenteral formulations for enhanced efficacy in acute inflammatory pain syndromes, particularly where rapid and multimodal analgesia is required[1][4].

Brand names

Dexalgen

Other names

metamizole + dexamethasone + hydroxocobalamin