Drug intelligence / Profile preview

dexamethasone + iron isomaltoside

Development stage
Unknown
Lead developer
Pharmacosmos
Modality
Orthosteric Ligands → Classical Binding Small Molecules → Small Molecules, Biodegradable Polymers → Polymer-based Nanoparticles → Nanoparticles → Drug Delivery Systems
Administration
Intravenous
01

Overview

This drug is a fixed-dose combination of dexamethasone, a synthetic corticosteroid with potent anti-inflammatory and immunosuppressant properties, and iron isomaltoside, an intravenous iron preparation used to treat iron deficiency anemia. Dexamethasone acts by binding to the glucocorticoid receptor, modulating gene expression to suppress inflammation and immune responses[4][5][9]. Iron isomaltoside consists of iron(III) complexed with the carbohydrate isomaltoside 1000; it enables controlled release of bioavailable iron for erythropoiesis and replenishment of body stores[2][3]. The combination may be used in clinical scenarios where both anti-inflammatory effects and rapid correction of anemia are required (e.g., certain pregnancy complications or chronic diseases), though no widely marketed product under this exact combination name exists. Each component has established uses individually.

02

Targets

GR (Glucocorticoid receptor)

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