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Dexibuprofen is the S(+)-enantiomer of ibuprofen, a small molecule nonsteroidal anti-inflammatory drug (NSAID). It is used for pain control, particularly in conditions like osteoarthritis and acute low back pain, and for fever treatment in various infections. Clinical trials have investigated its safety and efficacy in adults and children, often comparing it to ibuprofen. Studies have shown it to have a better safety profile, particularly regarding gastrointestinal adverse events, while maintaining non-inferior efficacy compared to racemic ibuprofen. It is developed by companies such as Apsen Farmaceutica S.A., Gebro Pharma GmbH, and Aponia Laboratories, Inc.
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