dexketoprofen + paracetamol + tramadol

Pain-Relief Medication-Parc de Salut Mar refers to a specific multi-modal analgesic regimen consisting of dexketoprofen, paracetamol, and tramadol. This combination is utilized as a standardized pain management protocol for patients undergoing surgical interventions for massive rotator cuff tears, specifically reverse shoulder prosthesis and arthroscopic decompression. Dexketoprofen is a non-steroidal anti-inflammatory drug (NSAID) that provides analgesia by inhibiting cyclooxygenase enzymes (COX-1 and COX-2), thereby reducing prostaglandin synthesis. Paracetamol (acetaminophen) serves as a non-opioid analgesic and antipyretic with predominantly central effects. Tramadol is a centrally acting analgesic with a dual mechanism of action: it acts as a weak agonist at mu-opioid receptors and inhibits the neuronal reuptake of norepinephrine and serotonin. The combination of these three agents is designed to provide synergistic pain relief by targeting multiple physiological pathways involved in nociception and inflammation.