Drug intelligence / Profile preview

dexketoprofen + paracetamol + tramadol

Development stage
Unknown
Lead developer
Menarini
Modality
Small Molecules
01

Overview

Pain-Relief Medication-Parc de Salut Mar refers to a specific multi-modal analgesic regimen consisting of dexketoprofen, paracetamol, and tramadol. This combination is utilized as a standardized pain management protocol for patients undergoing surgical interventions for massive rotator cuff tears, specifically reverse shoulder prosthesis and arthroscopic decompression. Dexketoprofen is a non-steroidal anti-inflammatory drug (NSAID) that provides analgesia by inhibiting cyclooxygenase enzymes (COX-1 and COX-2), thereby reducing prostaglandin synthesis. Paracetamol (acetaminophen) serves as a non-opioid analgesic and antipyretic with predominantly central effects. Tramadol is a centrally acting analgesic with a dual mechanism of action: it acts as a weak agonist at mu-opioid receptors and inhibits the neuronal reuptake of norepinephrine and serotonin. The combination of these three agents is designed to provide synergistic pain relief by targeting multiple physiological pathways involved in nociception and inflammation.

Other names
Pain-Relief Medication-Parc de Salut Mar
02

Targets

SERT (Sodium-dependent serotonin transporter)PTGS2 (Prostaglandin-Endoperoxide Synthase 2)MOR (Mu opioid receptor)NET (Norepinephrine Transporter)PGHS-1 (Prostaglandin G/H Synthase 1)

Beyond the preview

Go deeper on dexketoprofen + paracetamol + tramadol.

Explore the evidence, development activity, and competitive landscape with Gosset’s full data platform.

Clinical trials

Full profile access

Follow clinical development from study design and recruitment through results.

  • Trial phase
  • Status
  • Readouts

Indications & development

Full profile access

Explore development by indication, patient population, and geography.

  • Indications
  • Development status
  • Countries

Licensing & deals

Full profile access

Trace asset ownership, licensing agreements, and commercial partnerships.

  • Partners
  • Deal terms
  • Milestones

Patents & exclusivity

Full profile access

Explore the patent landscape and regulatory exclusivity around an asset.

  • Patents
  • Expiration dates
  • Exclusivity

Competitive landscape

Full profile access

Compare development programs by target, modality, and indication.

  • Competing assets
  • Targets
  • Development stage

Research & analysis

Full profile access

Connect source evidence and development news to your research questions.

  • Publications
  • News
  • Analysis

Bring the full picture into focus.

See how Gosset can support your research on dexketoprofen + paracetamol + tramadol.

Explore the full profile

Gosset Free

Get started with Gosset.

Enter your work email and we’ll be in touch with next steps.

Work email preferred.

Book a call