dexproxibutene hemimaleate

Dexproxibutene hemimaleate (CIBA-44328) is a synthetic analgesic compound structurally related to dextropropoxyphene. It is the dextrorotary isomer of 2-(dimethylaminomethyl)-1,2-diphenyl-3-butene-2-ol proprionate in the maleate form. The drug was investigated as an oral analgesic for pain management in conditions such as rheumatoid arthritis and demonstrated intermediate efficacy between paracetamol and stronger agents like aspirin or codeine combinations. Its mechanism of action is presumed to be similar to other diphenylbutylamine derivatives (like dextropropoxyphene), acting primarily as a central nervous system depressant with opioid-like properties[6][7].

Other names

dexproxibutene maleateD-1,2-diphenyl-2-propionyloxy-3-(dimethylaminomethyl)-3-butene maleate