Drug intelligence / Profile preview

Dextiva CPM

Development stage
Unknown
Lead developer
Wonne International
Modality
Small Molecules
Administration
Oral
01

Overview

Dextiva CPM is an oral syrup combination product marketed by Wonne International, containing the antitussive dextromethorphan hydrobromide and the first-generation antihistamine chlorpheniramine maleate. Dextromethorphan suppresses the cough reflex by acting as an agonist at sigma-1 receptors in the medullary cough center of the central nervous system. Chlorpheniramine maleate acts as a competitive antagonist at H1 histamine receptors, thereby reducing allergic symptoms such as sneezing, rhinorrhea, and itchy/watery eyes. This combination is indicated for the symptomatic relief of cough and upper respiratory symptoms associated with the common cold, hay fever, or other respiratory allergies.

Brand names
Dextiva CPMDEXTIVA CPM Syrup
Other names
dextromethorphan + chlorpheniraminedextromethorphan / chlorpheniramine
02

Targets

SIGMAR1 (Sigma non-opioid intracellular receptor 1)HRH1 (Histamine H1 Receptor)

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